Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Another transistor-based revolution: on-chip qPCR

More than 40 years after the invention of semiconductor pH microtransducers known as ISFETs, this transistor-based technology may revolutionize quantitative PCR.

This is a preview of subscription content, access via your institution

Access options

Rent or buy this article

Prices vary by article type

from$1.95

to$39.95

Prices may be subject to local taxes which are calculated during checkout

Figure 1: The ISFET-qPCR device's potential for increased parallelism.

References

  1. Toumazou, C. et al. Nat. Methods 10, 641–646 (2013).

    Article  CAS  Google Scholar 

  2. Rothberg, J.M. et al. Nature 475, 348–352 (2011).

    Article  CAS  Google Scholar 

  3. Sedlak, R.H. & Jerome, K.R. Diagn. Microbiol. Infect. Dis. 75, 1–4 (2013).

    Article  CAS  Google Scholar 

  4. BlueSEQ. Life Technologies–Ion Torrent. Sequencing Knowledge Bankhttp://blueseq.com/knowledgebank/sequencing-platforms/life-technologies-ion-torrent/ (2012; accessed 6 June 2013).

  5. Vogelstein, B. & Kinzler, K.W. Proc. Natl. Acad. Sci. USA 96, 9236–9241 (1999).

    Article  CAS  Google Scholar 

  6. Heyries, K.A. et al. Nat. Methods 8, 649–651 (2011).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Carlotta Guiducci.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Guiducci, C., Spiga, F. Another transistor-based revolution: on-chip qPCR. Nat Methods 10, 617–618 (2013). https://doi.org/10.1038/nmeth.2525

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nmeth.2525

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing