Ph. Renaud is active in several scientific committee (scientific journals, international conferences, scientific advisory boards of companies, PhD thesis committee). He is also co-founder of the Nanotech-Montreux conference and founding member of MSN conference (which is now Nanotech in USA). Ph. Renaud is committed to valorization of basic research through his involvement in several high-tech start-up companies.
On-chip flow cytometry: We develop microfluidic devices to be used in fields as hematology, oncology and toxicology. Cell analysis and cell separation is performed by means of dielectrophoretic force spectroscopy in a microfluidic device by opposing forces at multiple frequencies discriminating cells types according to their dielectric properties.
Using on-chip flow cytometry, it is possible to measure cell characteristics and subsequently perform cell-sorting and cell lysis. This allows to define new diagnostic tools for diseases related to abnormal cell function or related to cell contamination.
Cell-based biosensors: We are are developing autonomous biosensing platforms, based on living cells, with the aim to use them as nodes of a sensor network system for environmental monitoring. Living cells are used in such a system as the sensor, and secondary probes measure in real time the cellular response to changing environmental conditions
A chip with genetically bacterial strains is developped for monitoring chemical componds in water
The goal of the project is the fabrication of a microfluidic system able to characterize different kinds of cells and more complex biological structures by dielectric spectroscopy. Cells are embedded in a hydrogel 3D scaffold and perfused through microchannels. Impedance spectroscopy measurements are performed using a dual interdigitated microelectrodes array
Cells culture chips: We work on news techniques to trap cells in polymer gels directly in a microchannel. This offers the possibility to generate gel structures with layers of different cells for the study of the biochemical environment on cells, cell-cell interactions and tissue engineering.
We have developed a chip aimed at develppmental biology experiments, in which the long term culture of dosiphila wing disk can be performed. This allows to get a better understanding of intercellular communication and of the influence of external parameters on the development of organs.
Nanofluidics: Our goal is to fabricate single nanopores and nanoporous membranes, to study the transport of biomolecules through them and to investigate how to modify the electrical double layer in the pores and how those modifications affect the transport.
Bioelectronic implants: Chemical stimulation of neural tissue is currently studied, by combining electrodes and microfluidic channels on flexible neural probes. The insertion of strain gauges and a wireless telemetry system in a knee prosthesis is studied, for the long term monitoring of ageing of such devices. We study new materials for microeletrode implants