Prof. Aleksandra Radenovic

Associate Professor

2008     Tenure-Track Assistant Professor of Bioengineering at the School of Engineering, EPFL
2007-July 2008    Visiting Scientist NIDCR at NIH  Institute Bethesda and HHMI Janelia Farm USA
2004-2007    Postdoctoral Fellow Department of Physics, University of California Berkeley,USA
December, 2003    PhD in Physics Laboratory of Physics of Living Matter, University of Lausanne
December, 1999    Diploma in Physics Department of Physics, Faculty of Science, University of Zagreb

News

Research Area

My lab works in the research field that can be termed single molecule biophysics. We develop techniques and methodologies based on optical imaging, biosensing and single molecule manipulation with the aim to monitor the behavior of individual biological molecules and complexes in vitro and in live cells. Our current research is focused on three major directions:

(i) Developing and using nanopores as platform for molecular sensing and manipulation. In particular we focus on solid-state nanopores realized either in glass nanocapillaries, or on suspended 2d-material membranes and standard silicon-nitride membranes. 

(ii) Studying how biomolecules function, especially how proteins and nucleic acids interact, using force-based manipulation single-molecule techniques, in particular optical tweezers, optical wrench system, Anti- Brownian Electrokinetic (ABEL) trap and combination of nanopore/nanocapillaries with OT. 

(iii) Developing super-resolution optical microscopy, based on single molecule localizations (SMLM) in cells with molecular-scale resolution, with an aim to extract quantitative information.     

Contact


Aleksandra RADENOVIC
EPFL STI IBI-STI LBEN
BM 2140 (Bâtiment BM)
Station 17
CH-1015 Lausanne