Séminaire distingués

Prof. Reza Ghodssi - IMT Distinguished Lecture

Prof. Dr. Reza Ghodssi
University of Maryland

Institute of Microengineering - Distinguished Lecture

Abstract & Bio to follow.

Note: The Seminar Series is eligible for ECTS credits in the EDMI doctoral program.

 


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HASEL Artificial Muscles - Versatile High-Performance Actuators for a New Generation of Life-like Robots

Prof. Dr. Christoph Keplinger
University of Colorado Boulder

Institute of Microengineering - Distinguished Lecture

Abstract: Robots today rely on rigid components and electric motors based on metal and magnets, making them heavy, unsafe near humans, expensive and ill-suited for unpredictable environments. Nature, in contrast, makes extensive use of soft materials and has produced organisms that drastically outperform robots in terms of agility, dexterity, and adaptability. The Keplinger Lab aims to fundamentally challenge current limitations of robotic hardware, using an interdisciplinary approach that synergizes concepts from soft matter physics and chemistry with advanced engineering technologies to introduce intelligent materials systems for a new generation of life-like robots. One major theme of research is the development of new classes of actuators – a key component of all robotic systems – that replicate the sweeping success of biological muscle, a masterpiece of evolution featuring astonishing all-around actuation performance, the ability to self-heal after damage, and seamless integration with sensing.

This talk is focused on the labs' recently introduced HASEL artificial muscle technology. Hydraulically Amplified Self-healing ELectrostatic (HASEL) transducers are a new class of self-sensing, high-performance muscle-mimetic actuators, which are electrically driven and harness a mechanism that couples electrostatic and hydraulic forces to achieve a wide variety of actuation modes. Current designs of HASEL are capable of exceeding actuation stress of 0.3 MPa, linear strain of 100%, specific power of 600W/kg, full-cycle electromechanical efficiency of 30% and bandwidth of over 100Hz; all these metrics match or exceed the capabilities of biological muscle. Additionally, HASEL actuators can repeatedly and autonomously self-heal after electric breakdown, thereby enabling robust performance. Further, this talk introduces a facile fabrication technique that uses an inexpensive CNC heat sealing device to rapidly prototype HASELs. New designs of HASEL incorporate mechanisms to greatly reduce operating voltages, enabling the use of lightweight and portable electronics packages to drive untethered soft robotic devices powered by HASELs. Modeling results predict the impact of material parameters and scaling laws of these actuators, laying out a roadmap towards future HASEL actuators with drastically improved performance. These results highlight opportunities to further develop HASEL artificial muscles for wide use in next-generation robots that replicate the vast capabilities of biological systems.

Bio: Christoph Keplinger is an Assistant Professor of Mechanical Engineering and a Fellow of the Materials Science and Engineering Program at the University of Colorado Boulder, where he also holds an endowed appointment serving as Mollenkopf Faculty Fellow. Building upon his background in soft matter physics (PhD, JKU Linz), mechanics and chemistry (Postdoc, Harvard University), he leads a highly interdisciplinary research group at Boulder, with a current focus on (I) soft, muscle-mimetic actuators and sensors, (II) energy harvesting and (III) functional polymers. His work has been published in top journals including Science, Science Robotics, PNAS, Advanced Materials and Nature Chemistry, as well as highlighted in popular outlets such as National Geographic. He has received prestigious US awards such as a 2017 Packard Fellowship for Science and Engineering, and international awards such as the 2013 EAPromising European Researcher Award from the European Scientific Network for Artificial Muscles. He is the principal inventor of HASEL artificial muscles, a new technology that will help enable a next generation of life-like robotic hardware; in 2018 he co-founded Artimus Robotics to commercialize the HASEL technology.

Note: The Seminar Series is eligible for ECTS credits in the EDMI doctoral program.


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CMOS Microelectronics for DNA detection using Ion-Sensitive Field Effect Transistors

Prof. Dr. Pantelis Georgiou
Imperial College London

Institute of Microengineering - Distinguished Lecture

Abstract: In the last decade, we have seen a convergence of microelectronics into the world of healthcare providing novel solutions for early detection, diagnosis and therapy of disease. This has been made possible due to the emergence of CMOS technology, allowing fabrication of advanced systems with complete integration of sensors, instrumentation and processing, enabling design of miniaturised medical devices which operate with low-power. This has been specifically beneficial for the application areas of DNA based diagnostics and full genome sequencing, where the implementation of chemical sensors known as Ion-Sensitive Field Effect Transistors (ISFETs) directly in CMOS has enabled the design of large-scale arrays of millions of sensors that can conduct in-parallel detection of DNA. Furthermore, the scaling of CMOS with Moore’s law and the integration capability with microfluidics has enabled commercial efforts to make full genome sequencing affordable and therefore deployable in hospitals and research labs.
 
In this talk, I present how my lab is advancing the areas of DNA detection and rapid diagnostics through the design of CMOS based Lab-on-Chip systems using ISFETs. I will first introduce the fundamentals and physical properties of DNA as a target molecule and how it can be detected using different modalities through the use of CMOS technology. I will then present methods of design of ISFET sensors and instrumentation in CMOS, in addition to the challenges and limitations that exist for fabrication, providing solutions to allow design of large-scale ISFET arrays for real-time DNA amplification and detection systems. I will conclude with the presentation of state-of-the-art CMOS systems that are currently being used for genomics and point-of-care diagnostics, and the results of our latest fabricated multi-sensor CMOS platform for rapid screening of infectious disease and management of antimicrobial resistance.

Bio: Pantelis Georgiou currently holds the position of Reader (Associate Professor) at Imperial College London within the Department of Electrical and Electronic Engineering. He is the head of the Bio-inspired Metabolic Technology Laboratory in the Centre for Bio-Inspired Technology; a multi-disciplinary group that invents, develops and demonstrates advanced micro-devices to meet global challenges in biomedical science and healthcare. His research includes ultra-low power micro-electronics, bio-inspired circuits and systems, lab-on-chip technology and application of micro-electronic technology to create novel medical devices. Application areas of his research include new technologies for treatment of diabetes such as the artificial pancreas, novel Lab-on-Chip technology for genomics and diagnostics targeted towards infectious disease and antimicrobial resistance (AMR), and wearable technologies for rehabilitation of chronic conditions.
 
Dr. Georgiou graduated with a 1st Class Honours MEng Degree in Electrical and Electronic Engineering in 2004 and Ph.D. degree in 2008 both from Imperial College London. He then joined the Institute of Biomedical Engineering as Research Associate until 2010, when he was appointed Head of the Bio-inspired Metabolic Technology Laboratory. In 2011, he joined the Department of Electrical & Electronic Engineering, where he currently holds an academic faculty position. He conducted pioneering work on the silicon beta cell and is now leading the project forward to the development of the first bio-inspired artificial pancreas for treatment of Type I diabetes. In addition to this, he made significant contributions to the development of integrated chemical-sensing systems in CMOS. He has pioneered the development of the Ion-Sensitive Field Effect Transistor, an integrated pH sensor which is currently being used in next generation DNA sequencing machines, demonstrating for the first time its use in low-power weak-inversion, and its capability in a multimodal sensing array for Lab-on-Chip applications. Dr. Georgiou is a senior member of the IEEE and IET and serves on the BioCAS and Sensory Systems technical committees of the IEEE CAS Society. He is an associate editor of the IEEE Sensors and TBioCAS journals. He is also the CAS representative on the IEEE sensors council. In 2013 he was awarded the IET Mike Sergeant Achievement Medal for his outstanding contributions to engineering and development of the bio-inspired artificial pancreas. In 2017, he was also awarded the IEEE Sensors Council Technical Achievement award. He is an IEEE Distinguished Lecturer in Circuits and Systems.

Note: The Seminar Series is eligible for ECTS credits in the EDMI doctoral program.


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Prof. Debbie Senesky - IMT Distinguished Lecture

Prof. Dr. Debbie Senesky
Stanford University

Institute of Microengineering - Distinguished Lecture

Abstract and Bio to follow.

Note: The Seminar Series is eligible for ECTS credits in the EDMI doctoral program.


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