Bioinstrumentation & Bioimaging

At EPFL, Bioinstrumentation and Bioimaging are key drivers of innovation in life sciences and biomedical engineering. Researchers design and develop cutting-edge instruments and imaging technologies to visualize and measure biological processes across scales—from molecules to entire organisms. These tools enable real-time, high-resolution insights into cellular function, disease progression, and therapeutic response. By integrating optics, electronics, microfluidics, and computation, EPFL is advancing the frontiers of biomedical diagnostics, neuroscience, and personalized medicine.

Key research themes

• Optical microscopy
• Super-resolution imaging
• Single-molecule imaging
• Electron microscopy
• Bio-AFM (atomic force microscopy)
• Microfluidics & lab-on-chip
• High-throughput imaging
• Biophotonics
• Integrated bioelectronics
• Nanofluidics

Professor with specific keywords

ALTUG Hatice

Nanophotonics, label-free biosensors, plasmonic imaging, optofluidics, single-molecule detection

D’ANGELO Giovanni

Lipid droplet dynamics, membrane remodeling, live-cell imaging, ER stress assays

DEPLANCKE Bart

Single-cell omics, spatial transcriptomics, high-content imaging, automated phenotyping

FANTNER Georg

High-speed AFM, correlative microscopy, nano-mechanical mapping, 3D cellular imaging

GENOUD Christel

Cryo-electron tomography, correlative EM, 3D ultrastructure imaging, volume EM

GUIDUCCI Carlotta

Electronic biosensors, impedance spectroscopy, bio-MEMS, integrated lab-on-chip systems

MAERKL Sebastian

Microfluidics, high-throughput imaging assays, single-cell time-lapse microscopy

MANLEY Suliana

Super-resolution microscopy, single-particle tracking, PALM/STORM, cytoskeletal dynamics

MERTEN Christoph

Microfluidic droplet systems, live-cell imaging, organoid screening, automated bioassays

PSALTIS Demetri

Computational optics, optofluidics, lensless imaging, nonlinear microscopy

RADENOVIĆ Aleksandra

Nanopore imaging, quantum sensing, label-free single-molecule detection, nanofluidic devices

RAMDYA Pavan

Neuroimaging in behaving animals, connectomics, optogenetics, light-sheet microscopy

ROKE Sylvie

Nonlinear optical microscopy, vibrational imaging, water structure, cell surface photonics

SCHOONJANS Kristina

Metabolic imaging, live-cell fluorescence imaging, hormone signaling reporters

STAHLBERG Henning

Cryo-EM, cryo-ET, membrane protein structure, in situ tomography